Dysregulation of PAD 4 - mediated Q : 1 ; 2 citrullination ; 3 of nuclear GSK 3 Q : 4 β activates TGF - β signaling and induces EMT in breast cancer cells

Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY 10065; Institute of Laboratory Medicine, Clinical Chemistry, and Molecular Diagnostics and LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103 Leipzig, Germany; Department of Cell and Developmental Biology, Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065; Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden; Center for Cell Engineering, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065; Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461; Department of Zoology and Physiology, University of Wyoming, Laramie, WY 82071; Department of Clinical Sciences and Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853; and Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104